Gremio can book their place in the next round of the Copa Libertadores with victory over Junior de Barranquilla tonight.
Gremio currently trail their visitors by five points in Group Two, with both sides having played four of their six scheduled games.
But they hold a three-point advantage over third-placed Leon De Huanuco, who have played a game more, meaning a draw against Junior De Baranquilla, who are already through, would be enough to ensure their progress.
While Gremio were held to a 1-1 draw by Leon Du Huanuco in their most recent outing in the competition, Junior de Baranquilla will be looking to record their fourth successive win in the group.
Watch Gremio v Junior de Barranquilla live at 365, kicking off at 23.15 GMT.